Isolation of Exosome Sub-subpopulation using
                                         Technology

Conventional immunoaffinity-based methods suffer from difficulties in overcoming the limit of detection and maintaining reproducibility due to interference from the matrix effect produced by the free substances unrelated to the target in body fluids
 

Early diagnosis of cancer is possible through the platform technology that can detect heterogeneous change of exosome surface biomarkers released into blood from cancer cells
 

We have developed                          , a novel isolation technique based on ‘Ca²⁺ switch-on/off binding reaction’ which enables to sequentially separate exosome species in sample toward two or more markers under mild conditions to achieve early diagnosis of cancer